The multi-target mechanism and therapeutic strategies of the anti-tumor effects of phytochemicals
1Liu Chenyu,2Ni Xiaorong,2Liang Yi
1Key Laboratory of Environmental Pollution and Disease Monitoring of Ministry of Education School of Public Health and Health
Sciences Guizhou Medical University Guiyang 550025 Guizhou China
2Department of Clinical Nutrition Affiliated Hospital of
Guizhou Medical University Guiyang 550004 Guizhou China
Abstract：In recent years cancer has become one of the major public health challenges worldwide due to its high incidence and
mortality rates. Traditional treatment methods such as surgery chemotherapy and radiotherapy have played significant roles in
tumor treatment but they still have notable side effects and strong drug resistance. Against this backdrop secondary metabolites from
plants have become a continuous research focus in the field of tumor chemoprevention and the development of new anti-cancer drugs
thanks to their natural biocompatibility multi - target regulatory properties and low systemic toxicity. This review systematically
summarizes the types of plant compounds their anti - tumor mechanisms applications in cancer prevention combined treatment
strategies and pharmacokinetic characteristics based on relevant research literature on plant compounds' anti - tumor effects and
discusses future research trends and challenges in clinical translation.
