Gastric cancer severely affects human health and has become a significant health issue of global concern. In its complex pathogenesis genetic regulatory networks play an important role. Among them the competitive endogenous RNA ceRNA regulatory network is an important field of research. This network involves the interaction between various types of RNA molecules including mRNA miRNA lncRNA and circRNA etc. They precisely control gene expression through complex regulatory mechanisms thereby affecting the occurrence and development of gastric cancer. Positive feedback loops are indispensable signaling mechanisms within biological systems they accelerate or amplify specific biological processes by cyclically enhancing initial signals. They play a crucial role not only in cell growth development and response to various physiological and pathological stimuli but also participate in the occurrence and development of tumors in many ways such as promoting the proliferation and invasion of tumor cells changing the tumor microenvironment and increasing the chemoresistance of tumor cells. Positive feedback loops also exist within the ceRNA regulatory network. These loops potentially drive the occurrence and development of gastric cancer by amplifying specific signals to regulate key processes such as cell proliferation apoptosis migration and invasion. Therefore in - depth study of the positive feedback loops related to the ceRNA regulatory network is of great significance for revealing the pathogenesis of gastric cancer and discovering new potential therapeutic targets. This article reviews the role and molecular mechanisms of ceRNA - related positive feedback loops in gastric cancer and looks forward to their application prospects in the treatment of gastric cancer.