Nutrition impact symptoms NIS encompass a series of clinical symptoms that can negatively affect the nutritional status of patients by impairing food intake and nutritional status. Cancer itself and / or related treatments can impact food digestion and absorption leading to NIS including nausea vomiting abdominal pain and diarrhea. The incidence of one or more NIS in cancer patients can be as high as 64% resulting in reduced food intake and deficiencies in energy protein and micronutrients. This in turn leads to weight loss and overall functional impairment ultimately triggering nutrition-related complications that negatively affect disease prognosis and clinical outcomes. This article focuses on nine common NIS associated with the digestive system in cancer patients and provides guidance and recommendations from a nutritional therapy perspective to support clinical treatment.