744 例住院老年肿瘤患者营养不良状况调查及分析

谢林颖,王畅,吴海涛,王轶卓,梁婷婷,何华,姚程,李薇

肿瘤代谢与营养电子杂志 ›› 2018, Vol. 5 ›› Issue (4) : 380-386.

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肿瘤代谢与营养电子杂志 ›› 2018, Vol. 5 ›› Issue (4) : 380-386. DOI: 10.16689/j.cnki.cn11-9349/r.2018.04.010
论著

744 例住院老年肿瘤患者营养不良状况调查及分析

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The analysis and the investigation of malnutrition in 744 elderly inpatients with tumor

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摘要

目的 调查本院住院老年恶性肿瘤患者营养不良的发生情况,进一步分析其与不同临床因素的相关性。方法  采 用横断面调查法,应用PG-SGA对我院住院老年恶性肿瘤患者进行营养不良筛查与评估,分析营养状况与年龄、肿瘤分期、 治疗手段、住院时间及费用等临床因素的相关性。结果(1)老年恶性肿瘤患者744例,营养不良发生率高达67.9%;(2) 老年胃肠道恶性肿瘤患者发生轻/ 中度营养不良及重度营养不良比率均明显高于非胃肠道恶性肿瘤患者,分别为81.9% vs 58.2%,40.5% vs 22.7%,P 值均<0.001;(3)老年胃肠道恶性肿瘤患者营养状况与临床因素相关性分析:①年龄:营养 不良发生率与年龄因素无明显相关性,P=0.462;②临床分期:Ⅰ+Ⅱ期患者营养不良发生率为79.3%(88/111),Ⅲ期为 88.8%(103/116),Ⅳ期为87.5%(42/48),P=0.595,无统计学差异;③治疗手段:接受化疗患者(236 例)营养不良发 生比率明显高于仅接受手术患者(37 例),86.0% vs 64.9%,P=0.001;④住院费用:无营养不良、轻/ 中度营养不良和重 度营养不良患者中位住院费分别为12,420.15 元、15,384.20 元、20,672.70 元,P=0.004,重度营养不良患者住院费用明显高 于前两者;⑤住院时间:无营养不良、轻/中度营养不良和重度营养不良患者中位住院时间分别为6.50天、7.50天和14.00天, P=0.002,重度营养不良患者住院天数明显多于前两者。结论 ①老年肿瘤患者营养不良现象普遍存在,尤以胃肠道肿瘤为著; ②老年肿瘤患者合并营养不良会明显增加住院费用、延长住院时间;③不同治疗手段对营养状态存在不同程度的影响,应 权衡利弊,合理应用;④关注老年肿瘤患者的营养状况,及早筛查、及时干预。

Abstract

Objective It was investigated the incidence of malnutrition in elderly patients with malignant tumor in our hospital, and further analyzed the correlation among malnutrition and different clinical factors. Methods PG-SGA was determined for the cancer inpatients in our hospital, then we analyzed the relativities among the age、stages、therapy、length of stay (LOS)、cost and other clinical factors. Results (1)The incidence of malnutrition was up to 67.9% in these 744 elderly inpatients; (2)Compared with non-gastrointestinal cancer patients, the incidence of malnutrition (81.9% vs 58.2%) and severe-malnutrition(40.5% vs 22.7%) increased significantly in patients with gastrointestinal cancer (P<0.001). (3)Correlation analysis of nutritional status and clinical factors in elderly patients with gastrointestinal malignant tumor: ①According to the Stratification by using age factors, malnutrition rates were no significant difference in patients (P=0.462); ②Different stages (TNM) didn’t show any difference on nutritional status (P=0.595), The malnutrition incidence of Stage Ⅰ+Ⅱ patients was 79.3% (88/111), and Stage Ⅲwas 88.8% (103/116), Stage Ⅳ was 87.5% (42/48); ③ Compared with chemotherapy (236 cases) , elderly cancer patients with surgery (37cases) had a lower rate of malnutrition (86.0% vs 64.9%, P=0.001); ④The median costs of hospitalization for patients with severe malnutrition (20672.70 yuan) were significantly higher than those without malnutrition(12420.15 yuan) or mild / moderate malnutrition (15384.20 yuan), P=0.004, and there was no significant difference in between the latter; ⑤The median length of stay for patients with severe malnutrition (14.00 days) were significantly higher than those without malnutrition (6.50 days) or mild / moderate malnutrition (7.50 days), P=0.002, and there was no significant difference in between the latter. Conclusion: ①Malnutrition is common in elderly patients with malignant tumors, especially in gastrointestinal cancers; ②The elderly cancer patients with severe malnutrition will significantly increase the cost of hospitalization and the length of stay; ③Different treatments have different effects on nutritional status, so we should judge and weigh the advantages and disadvantages and choose the right treatment; ④We should pay more attention to the nutritional status of elderly cancer patients, and it’s important early screening and timely intervention.

关键词

老年恶性肿瘤患者 / 营养不良 / 患者主观整体评估

Key words

Elderly cancer patients / Malnutrition / Patient-generated subjective global assessment

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谢林颖,王畅,吴海涛,王轶卓,梁婷婷,何华,姚程,李薇. 744 例住院老年肿瘤患者营养不良状况调查及分析[J]. 肿瘤代谢与营养电子杂志. 2018, 5(4): 380-386 https://doi.org/10.16689/j.cnki.cn11-9349/r.2018.04.010
XIE Lin-ying, WANG Chang, WU Hai-tao, WANG Yi-zhuo, LIANG Ting-ting, HE Hua, YAO Cheng, LI Wei. The analysis and the investigation of malnutrition in 744 elderly inpatients with tumor[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2018, 5(4): 380-386 https://doi.org/10.16689/j.cnki.cn11-9349/r.2018.04.010

基金

吉林省卫生厅基金项目(2017J063)

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