论著

持续与间歇肠内营养治疗对放化疗患者营养状态的影响

  • 王璐 ,
  • 孙爱民
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  • 南方医科大学南方医院放疗科,广州 510515

网络出版日期: 2021-04-12

Effect of continuous and intermittent enteral nutrition on nutritional status in patients with radiotherapy and chemotherapy

  • WANG Lu ,
  • SUN Ai-min
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  • Department of Radiotherapy, Nanfang Hospital, Guangzhou 510515, Guangdong, China

Online published: 2021-04-12

摘要

目的 研究持续肠内营养治疗与间歇肠内营养治疗对放化疗患者的营养状态进行综合的对比分析。方法 采用等距随机抽样法将我院放疗科2016 年 6 月 ~2017 年 6 月收治的100 例放化疗患者随机分为接受间歇肠内营养治疗的对照组 以及接受持续肠内营养治疗的观察组各 50 例,对两组营养状态影响效果进行对比研究。结果 干预前对照组和观察组患者 PG-SGA 评分、生化指标无明显差异,干预后各指标数值均显示出不同程度差异性,并且观察组改善效果优于对照组,差 异有统计学意义(P < 0.05)。结论 相较于间歇肠内营养治疗,持续营养治疗更有助于改善放化疗患者营养状态,提高其 机体耐力水平,也有助于提高患者免疫力,从而缩短患者在放化疗周期内恢复各种组织功能所需要的时间,避免和减少由于营养不良而发生的并发症,减少住院天数,节约患者成本,避免由于营养不良造成的疗程中断,可作为临床优选方案推广使用。

本文引用格式

王璐 , 孙爱民 . 持续与间歇肠内营养治疗对放化疗患者营养状态的影响[J]. 肿瘤代谢与营养电子杂志, 2018 , 5(3) : 279 -282 . DOI: 10.16689/j.cnki.cn11-9349/r.2018.03.012

Abstract

Objective To compare the nutritional status of patients undergoing chemoradiotherapy with continuous enteral nutrition therapy and intermittent enteral nutrition therapy. Methods 100 cases of radiotherapy and chemotherapy were randomly divided into the control group receiving intermittent enteral nutrition therapy and the observation group receiving continuous enteral nutrition therapy in the department of radiotherapy from June 2016 to June 2017. The effects of nutritional status in the two groups were compared. Results There were no significant difference in PG-SGA scores and biochemical indexes between the two groups before intervention, and the difference between the indexes after intervention was statistically signifcant (P<0.05), and the improvement effect of the observation group were better than those of the control group. Conclusions Compared with intermittent enteral nutrition therapy, continuous nutritional support was more helpful to improve the nutritional status of patients with chemotherapy and to improve the level of endurance of the body. It also helps to improve the immunity of the patients, thus shortening the time needed to restore the function of various tissues during the radiotherapy and chemotherapy cycle, to avoid and to reduce complications, to reduce the number of days in hospital, to save the cost for the patients and to avoid the middle end of the course due to malnutrition. It can be used as a clinical selection scheme.
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