Research progress on the relationship between vitamin B6 and lung cancer

Liu Caiping; Wei Lei; Liu Yanqing

doi:10.16689/j.cnki.cn11-9349/r.2020.01.020

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Electronic Journal of Metabolism and Nutrition of Cancer ›› 2020, Vol. 7 ›› Issue (1) : 112-116. DOI: 10.16689/j.cnki.cn11-9349/r.2020.01.020

Research progress on the relationship between vitamin B6 and lung cancer

Liu Caiping, Wei Lei, Liu Yanqing

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Abstract

At present, lung cancer is a malignant cancer with high incidence and mortality rate which threatens human health. System management and comprehensive treatment including nutritional treatment are particularly important. Vitamin B6, as one of the most important B vitamins, is widely involved in body synthesis and metabolic reactions. However, the role of vitamin B6 in the occurrence, development, and treatment of different diseases is not fully understood. In this study, the effects of vitamin B6 on the risk and progression of lung cancer were discussed, and whether the demand of vitamin B6 would change in different stages of the occurrence, progression and treatment of lung cancer was understood. Combining these studies, we draws the following points： 1. The level of serum vitamin B6 was negatively correlated with the risk of lung cancer. However, for healthy or non-lung cancer people, dietary or vitamin B6 supplement could not reduce the risk of lung cancer, and high dose vitamin B6 supplementation might be harmful. 2. When the body is significantly deficient in vitamin B6, the risk of lung cancer increases. 3. For cancer patients, vitamin B6 alone or in combination with other nutrients can inhibit the proliferation and migration of cancer cells, induce the production of anti-tumor cytokines, and play an anti-tumor role. Therefore, the intake and supplement of vitamin B6 should first evaluate the health status of the body, especially the level of vitamin B6.

Key words

Vitamin B6 / Lung cancer / Pyridoxal phosphate / Pyridoxal kinase / Cisplatin

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Liu Caiping, Wei Lei, Liu Yanqing. Research progress on the relationship between vitamin B6 and lung cancer[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2020, 7(1): 112-116 https://doi.org/10.16689/j.cnki.cn11-9349/r.2020.01.020

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