Effect of depression on nutritional status of patients with nasopharyngeal carcinoma receiving radiotherapy

Zheng Xianbin; Gao Jin; Hua Lei; Guo Weiqian2; Tao Zhenchao; Zhang Yangyang

doi:10.16689/j.cnki.cn11-9349/r.2020.02.013

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Electronic Journal of Metabolism and Nutrition of Cancer ›› 2020, Vol. 7 ›› Issue (2) : 204-208. DOI: 10.16689/j.cnki.cn11-9349/r.2020.02.013

Effect of depression on nutritional status of patients with nasopharyngeal carcinoma receiving radiotherapy

Zheng Xianbin1， 3，Gao Jin3，Hua Lei2， 3，Guo Weiqian2， 3， Tao Zhenchao3，Zhang Yangyang3

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Abstract

Objective To evaluate the effect of depressive symptoms on the nutritional status of patients with nasopharyngeal carcinoma receiving radiotherapy. Methods According to the evaluation results of the HAD scale before radiotherapy， 77 patients with nasopharyngeal carcinoma who met the inclusion criteria were divided into the depressive group and the non-depressive group. Observe and evaluate the nutritional status changes of depression group （n=32） and non-depression group （n=45） before radiotherapy and the end of radiotherapy， and analyze the effect of depression on the nutritional status of patients. Results In this study， we found that about 41.6% of patients had depressive symptoms before radiotherapy. The average serum albumin and hemoglobin levels in the depression group at the end of radiotherapy were significantly lower than those in the non-depression group［（38.5±5.8） mg/dl vs （41.0±5.2） mg/dl，P=0.045；（108.3±31.6）g/L vs （111.6±16.6）g/L，P=0.041］， patients in depression group were more prone to weight loss ≥5%， BMI<18.5kg/m2 and NRS 2002 score ≥3 （75.0% vs 33.3%）， P=0.001； 28.1% vs 8.9%， P=0.026； 46.9% vs 17.8%， P=0.006）. Conclusion The depressive symptoms of patients with nasopharyngeal carcinoma are closely related to their nutritional status. In patients with nasopharyngeal carcinoma receiving radiotherapy， depressive symptoms may be used as predictors of malnutrition.

Key words

Nasopharyngeal carcinoma / Depressive symptoms / Nutritional status / Radiotherapy

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Zheng Xianbin，Gao Jin，Hua Lei，Guo Weiqian2， Tao Zhenchao，Zhang Yangyang. Effect of depression on nutritional status of patients with nasopharyngeal carcinoma receiving radiotherapy[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2020, 7(2): 204-208 https://doi.org/10.16689/j.cnki.cn11-9349/r.2020.02.013

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