Metabolic disorder in MBO

Luo Guijuan; Miao Mingyong

doi:10.16689/j.cnki.cn11-9349/r.2020.03.004

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Electronic Journal of Metabolism and Nutrition of Cancer ›› 2020, Vol. 7 ›› Issue (3) : 267-271. DOI: 10.16689/j.cnki.cn11-9349/r.2020.03.004

Metabolic disorder in MBO

Luo Guijuan1, Miao Mingyong2

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Abstract

Malignant bowel obstruction is malignant tumor associated intestinal obstruction common in patients with advanced ovarian cancer or gastrointestinal cancer. It’s one of the most lethal complications caused by tumor compression, tumor cell infiltration of autonomic nerves, paraneoplastic syndrome, or drug related factors. In this review, we delineate the current studies on metabolic disorders and mechanisms of malignant bowel obstruction at home and abroad and draw the following conclusions. Malignant bowel obstruction not only causes metabolic disorders of macronutrients such as glucose, protein, and fatty acids, but also causes micronutrients disorders. Intestinal dysfunction, inflammation and intestinal flora disorders, and lack of effective nutrition support contribute to the occurrence of malignant bowel obstruction. Metabolic disorders could aggravate obstruction and closely related to the prognosis. Clinical decision-making should pay attention to the metabolic situation. Recognizing the significant influence on the prognosis of patients, doctors should take active treatment to the metabolic disorder and improve quality of life.

Key words

Malignant bowel obstruction｜Macronutrients metabolic disorders｜Micronutrients metabolic disorders｜Inflammation｜Intestinal flora disorders / Nutritional support

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Luo Guijuan, Miao Mingyong. Metabolic disorder in MBO[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2020, 7(3): 267-271 https://doi.org/10.16689/j.cnki.cn11-9349/r.2020.03.004

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