Characteristics of malnutrition in malignant cancer patients

Chinese Society of Nutritional Oncology

doi:10.16689/j.cnki.cn11-9349/r.2020.03.006

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Electronic Journal of Metabolism and Nutrition of Cancer ›› 2020, Vol. 7 ›› Issue (3) : 276-282. DOI: 10.16689/j.cnki.cn11-9349/r.2020.03.006

Characteristics of malnutrition in malignant cancer patients

Chinese Society of Nutritional Oncology

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Abstract

There are significant differences between malnutrition caused by malignant tumors and benign diseases, which are manifested in the following seven aspects. ① the incidence of malnutrition is higher, 79.4% of inpatients with tumor have different degrees of malnutrition；② resting energy expenditure is increased: the energy expenditure of different tumors and different stages of the same tumor is different, but on the whole, the resting energy expenditure of patients with tumor increased by 10% on average, and the special glucose metabolism made the patients consume additionally about 300kcal energy every day；③ sustained physiological and psychological stress: the diagnosis of cancer itself, accompanying symptoms and treatment all brought huge trauma and stress to the patients body and mind；④ chronic low-grade irreversible inflammation: the nature of cancer is chronic low degree irreversible inflammation；its malnutrition is a kind of disorder accompanied by inflammatory reaction, that is, cachexia；⑤ wasting metabolic disorder: as a metabolic disease, malignant tumor is different from that of normal cells in the metabolism and metabolic reprogramming. Under the effect of inflammatory mediators and metabolic factors, there is significant wasting metabolic disorder；⑥ significant muscle loss: due to inflammatory reaction and catabolism, the whole body muscle loss of patients with malignant tumors are important reasons for weight loss；⑦ treatment is more difficult: it often requires more comprehensive treatment, especially metabolic modulation treatment. The more malignant the tumor is, the more obvious the above characteristics are. Malnutrition of malignant tumor has significant characteristics, so its treatment is also significantly different from that of benign diseases.

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Chinese Society of Nutritional Oncology. Characteristics of malnutrition in malignant cancer patients[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2020, 7(3): 276-282 https://doi.org/10.16689/j.cnki.cn11-9349/r.2020.03.006

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