The latent profile of nutritional status deterioration in patients with advanced tumors and its relationship with unmet needs

Wu Jianxia; Zhu Xiangyang; Zhou Yang; Wu Yu

doi:10.16689/j.cnki.cn11-9349/r.2026.01.017

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Electronic Journal of Metabolism and Nutrition of Cancer ›› 2026, Vol. 13 ›› Issue (1) : 126-133. DOI: 10.16689/j.cnki.cn11-9349/r.2026.01.017

Original Articles

The latent profile of nutritional status deterioration in patients with advanced tumors and its relationship with unmet needs

Wu Jianxia, Zhu Xiangyang, Zhou Yang, Wu Yu

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Abstract

Objective To explore the latent profile categories of nutritional status deterioration in patients with advanced tumors, analyze the influencing factors of different categories, and investigate their correlation with unmet needs, providing new ideas for improving the level of unmet needs in patients in the later stage. Method Patients with advanced tumors admitted to the Department of Oncology of Nantong Cancer Hospital from January to December 2024 were selected as the research objects. The enrolled research objects were investigated with the malignant assessment of nutritional status scale and the brief unmet needs questionnaire. Result 178 valid questionnaires were collected (92.71%). The score of deterioration of nutritional status in patients with advanced tumors was (8.45±1.61) points, and the score of unmet needs was (65.60±8.24) points. The deterioration of nutritional status in patients with advanced tumors was classified into three latent profile categories: high, medium and low deterioration of nutritional status groups. There were significant differences among the three category groups in terms of age (χ²=15.639, P=0.004), number of comorbidities (χ²=6.980, P=0.031), BMI (χ²=12.179, P=0.016), and social support (χ²=10.367, P=0.035). Logistic regression analysis showed that age, the number of comorbidities, BMI and social support were the influencing factors of deteriorating nutritional status (P < 0.05). The results of the difference analysis show that: There were significant differences in unmet needs among the groups of patients with advanced tumors in different profiles (F=22.149, P < 0.01). The level of unmet needs of patients in the high nutritional status deterioration group was significantly higher than that in the medium nutritional status deterioration group (P < 0.01) and the low nutritional status deterioration group (P < 0.01). The level of unmet needs in the middle nutrition deterioration group was significantly higher than that in the low nutrition deterioration group (P < 0.01). Conclusion The deterioration of nutritional status in different profiles is closely related to the level of unmet needs of patients. Clinical staff should promptly identify the risk profile of nutritional deterioration in patients and implement individualized nutritional support and psychosocial intervention at an early stage, which is the key to improving the needs and quality of life of patients with advanced tumors.

Key words

Advanced tumor / Deterioration of nutritional status / Nutritional therapy / Unmet requirements / Hospice care / Profile / Influencing factors / Relevance

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Wu Jianxia, Zhu Xiangyang, Zhou Yang, Wu Yu. The latent profile of nutritional status deterioration in patients with advanced tumors and its relationship with unmet needs[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2026, 13(1): 126-133 https://doi.org/10.16689/j.cnki.cn11-9349/r.2026.01.017

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