Research progress on pharmacological activities of bioactive constituents of red raspberry

ZHANG Hao-peng; LV Qiang; LIU Ming

doi:10.16689/j.cnki.cn11－9349/r.2019.04.002

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Electronic Journal of Metabolism and Nutrition of Cancer ›› 2019, Vol. 6 ›› Issue (4) : 396-400. DOI: 10.16689/j.cnki.cn11－9349/r.2019.04.002

Research progress on pharmacological activities of bioactive constituents of red raspberry

ZHANG Hao-peng, LV Qiang, LIU Ming

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Abstract

The red raspberry is a rubus of the rose family. It contains varieties of nutrients as well as biological active substances, and is beneficial to human health. Therefore, its called the golden fruit. Long-term consumption of red raspberries can reduce the risk of many chronic diseases and play therapeutic roles. Oxidative stress and inflammatory reaction can be inhibited by red raspberry. And it can also regulate endothelial function. Thus, it retards or treats cardiovascular and cerebrovascular diseases. Inhibiting the activity of α-amylase and α-glucosidase, red raspberry can reduce the absorption of glucose after meals. Red raspberry contains a lot of dietary fiber and phenolic active substances, which can regulate lipid metabolism. Anti-inflammatory effects are mainly achieved by reducing LDL and lipid oxidation, DNA damage, the production ROS, and NO, and increasing antioxidant enzyme activity. Antitumor mechanism mainly includes the scavenging ROS to prevent DNA oxidative damage, inhibiting the formation of DNA adduct, strengthening the DNA repair capacity, as well as regulating cell proliferation, apoptosis signaling pathways. This article reviews the pharmacological roles of red raspberry in heart cardiovascular and cerebrovascular diseases, diabetes, obesity, inflammation, tumor and other diseases.

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Red raspberry / Bioactive constituents / Pharmacological action

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ZHANG Hao-peng, LV Qiang, LIU Ming. Research progress on pharmacological activities of bioactive constituents of red raspberry[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2019, 6(4): 396-400 https://doi.org/10.16689/j.cnki.cn11－9349/r.2019.04.002

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