Abstract: The incidence rate of malnutrition in patients with acute leukemia is quite high, many patients need nutritional intervention during the treatment. However, only a few number of current studies focus on nutritional status of patients with acute leukemia. Furthermore, these studies are limited to the application of BMI toanalysize the nutritional status and prognosis, and many studies have not been consistent. PG-SGA is the preferred method for nutritional screening of cancer patients, recommended by ASPEN (American Society for Parenteral and Enteral Nutrition). It is widely used in solid tumors to evaluate patients’nutritional status by qualitative and quantitative analysis, but it is seldom applied in acute leukemia. In this review, we’re going todiscuss the current situation of nutritional status assessment in acute leukemia patients, illustrating the necessity of analyzing nutritional status in these patients and the indicators that can be applied in the future.