Objective The occurrence of cancer is increasing worldwide. It is known that diet and life style play important roles
in the incidence and progression of cancer. This review provided an overview of the association between vitamin D and cancer risk
and prognosis. Methods The published literatures about vitamin D and cancer risk and prognosis, especially Meta analysis, were
recruited for further comprehensive summary. Results Vitamin D status was inversely associated with colorectal cancer, breast
cancer, lung cancer and bladder cancer risk, and could improve the prognosis of hematological malignancies patients, however, the
association between vitamin D and risk of other cancers is still inconclusive. Conclusions Adequate vitamin D status is associated
with a lower risk of cancer, and can improve prognostic outcomes of cancer patients. More well-designed epidemiological studies are
needed for further investigation of the relationship between vitamin D and risk and prognosis of cancer.