With the development of medical technology and length of hospital stay reduced home nutrition is widely acceptd by patients. As malnutritional patients are often accompanied with complex clinical condition, some problemes needed to be soved urgently, i.e., how to implement normalized HEN, which can improve the effect and efficiency of home nutrition, and can reduce the complications of nutritional therapy. By searching literatures related about nutrition therapy through Pubmed, Embase and CNKI, combined with our HN work experiences, results showed that HEN not only reduced weight loss of patients and complications of HEN, but also improved the satisfaction of patients, by establishing NST (including physicians, dieticians, nurses, pharmacists, etc.) , making regulations and procedures of nutrition therapy and follow-up. HEN interview through outpatient service, telephone or APP is the key process of cancer patients' nutrition management, which is beneficial to find and solve the problems timely during the process of HEN, improve patients' compliance and curative effect. Planed, repeated and progressive nutrition education and nutrition management by NST, combined with professional and individualized nutrition counseling, could make patients understand the purpose and significance of nutritional therapy, improve significantly the patient's health behavior and compliance to nutrition therapy. Home nutrition under the guidance of NST is the extension of hospital nutrition therapy, and it’s beneficial to improve the effectiveness and security of nutritional therapy. HEN has been shown good cost effectiveness in developed countries, while in developing countries, more researches need to be done.