Objective To investigate the knowledge⁃attitude⁃practice(K⁃A⁃P) of cancer nutrition among 470 medical staffs in Hebei area, and analyze its influencing factors, to provide the scientific basis for make measures and further cancer nutrition work. Methods From December 2018 to June 2019, a self⁃designed questionnaire was used to investigate the K⁃A⁃P among 470 medical staffs in 13 Heibei hospital by the convenient sampling method, and statistical analysis based on collected scores. Results 481 questionnaires were sent out, 481 were recollected, finally 470 were effective, the effective rate was 97.77%. There were 240 doctors, 170 nurses, and 60 other medical staffs, the scores of overall K、A and P were 31.06±13.82、115.22±12.24 and 116.01±18.48, only 48.94%、53.19% and 46.17% of medical staffs were above the average. Spearman rank correlation showed, attitude was positively related with practice. Factors of knowledge score were sexual, occupation, academic, professional, teaching function, hospital nature and grade；factors of attitude score were occupation, academic, speciality, work type, teaching function、hospital grade；factors of practice score were occupation, academic, professional, working years, work type, hospital grade. Conclusion The medical staffs have a positive and rigorous attitude towards cancer nutrition in Hebei area, and it is necessary to strengthen the nutritional knowledge and nutritional behavior, by strengthening the construction of clinical nutrition and clinical nutritional department voluntary contact the superiority disciplines to optimize the work for cancer nutrition.