The multi⁃trace elements injection could provide many trace elements for human body, such as iron, zinc, copper, manganese, cobalt, fluorine, iodine, selenium, molybdenum and chromium, and is widely used in patients who need parenteral nutrition. To further improve the clinician′s understanding of multi⁃trace elements injection and better guide the rational clinical application, we invite the national expert group members to formulate a consensus paper. The consensus paper is a composite of systematically reviewing pertinent literature, Chinese clinical practice, and multiple sessions of debate, discussion, and composition, with reference to guidelines from European Society for Parenteral and Enteral Nutrition (ESPEN) and American Society for Parenteral and Enteral Nutrition (ASPEN). This consensus is based on clinical research evidences and experts′ experience, which will provide references for the clinical use of multi⁃trace elements injection in critically illness, moderate to severe burn, perioperative period, cancer, elderly, dialysis, intestinal fistula and short bowel syndrome.