If there are no special abnormalities in the digestive system of critically ill patients, it is recommended to start enteral nutrition from 24 to 48 hours after admission to the ICU, but the incidence of diarrhea in critically ill patients during enteral nutrition is rather high, which caused loss of nutrients, disturbance of water⁃electrolyte acid⁃base balance, and even forced interruption of enteral nutrition.It often leads to adverse clinical outcomes, increasing the length of hospital stay and mortality.The pain and economic burden it brings to patients cannot be ignored.Currently, most of the epidemiological studies on diarrhea in critically ill patients come from abroad, which cannot fully reflect the actual situation in China; there is still lack of unified diagnostic and evaluation standards;EN diarrhea is a comprehensive result of many factors, the condition of critically ill patients is complex, and we are still facing great challenges in its prevention and treatment.To ensure the safety of enteral nutrition treatment, the medical staff must have the awareness of risk assessment, monitor the risk factors and assess gastrointestinal function dynamically, then formulate personalized and reasonable nutrition programs to minimize the incidence of EN diarrhea.Therefor, the article summarized the definition、assessment tools、risk factors、nursing and treatment strategies of enteral nutrition⁃related diarrhea in critically patients in recent years.Aiming to provide reference for medical staff to scientifically implement enteral nutrition，reduce the incidence of enteral nutrition⁃related diarrhea in critically ill patients, and improve the effect of feeding.