Liver cancer is one of the most common malignant tumor that occurs in digestive system. Liver cancer is the 4th in morbidity and 2nd in mortality in China, which is a seriously endanger people's health and life. Malnutrition occurs throughout the entire course of liver cancer and the incidence of malnutrition is 80%. Patients often experience muscle protein consumption and decreased oxidation of branched amino acids, especially protei⁃energy malnutrition. For the diagnosis of malnutrition, liver cancer patients need routine nutritional diagnosis (nutrition screening, nutritional assessment and comprehensive assessment) when they are admitted to hospital, and follow the five⁃step principle for nutrition intervention. Optimal daily energy intake should not be lower than 30-35 kcal/kg, optimal daily protein intake should not be lower than 1.2-1.5 g/kg. For patients with hepatic encephalopathy need to reduce protein intake as appropriately and select protein sources reasonably. Patients with liver cancer with metabolic disorders and multiple organ dysfunction require multidisciplinary treatment and adhere to full nutritional management. Liver cancer patients which undergo liver resection, liver transplantation and interventional treatment have various nutritional problems, also accompanied by liver cirrhosis, hepatic encephalopathy, sarcopenia and sarcopenic obesity, individualized nutritional therapy in different disease states have a positive effect on the quality of life and prognosis of liver cancer patients. This article summarizes the nutritional therapy of patients with liver cancer in different clinical disease states to improve the prognosis of patients with liver cancer.