Objective To investigate the nutritional status of hospitalized patients with common cancer and influencing factors. Method From January 2018 to December 2019, we enrolled 1385 patients with cancer hospitalized for treatment in First Affiliated Hospital of Kunming Medical University. These patients were diagnosed with malignant tumors by pathologically. Demographic data, anthropometric measurements and laboratory examination within 48 hours of admission were collected, patient⁃generated subjective global assessment (PG⁃SGA) was used to evaluate the nutritional status and influencing factors of nutritional status were analyzed. Result There are 980 males (70.8%) and 405 females (29.2%), and average age of (56.5±13.4) years in our 1385 cases. The average PG⁃SGA score was (6.92±5.27), with PG⁃SGA score as standard, 203 patients (14.7%) had the good nutrition, 279 patients (20.1%) were mild malnutrition, 429 patients (31.0%) were moderate malnutrition, 474 patients (34.2%) were severe malnutrition. 23.0% (319/ 1385) of patients received enteral nutritional therapy, 36.6% (507/1385) received parenteral nutritional therapy, 7.1% (99/1385) received enteral and parenteral nutritional therapy. After controlling for confounding factors, Logistic regression analysis demonstrates that age (≥70 years old), male, tumor metastasis, weight loss in the recent 1-3 months and diet loss in the recent 1 week were risk factors for malnutrition. Higher serum albumin, hemoglobin and hand grip strength were protective factors for malnutrition, the differences were statistically significant (P<0.05). Conclusion With PG⁃SGA score as standard, 85.3% of the cancer patients were malnutrition and 65.2% of them were moderate/severe malnutrition, and there was a low rate of nutritional treatment. Patients with age (≥70 years old), male, tumor metastasis, weight loss in the recent 1⁃3 months and diet loss in the recent 1 week are likely to have malnutrition. Patients with higher serum albumin, hemoglobin and hand grip strength have less malnutrition.