Malnutrition is common in hospitalized patients especially in critically ill and cancer patients. Malnutrition can lead to further deterioration of the patient's condition prolong the length of hospital stay and even increase the risk of poor prognosis. Therefore nutritional support for these patients is very necessary. Enteral nutrition is the first choice for malnourished patients with normal gastrointestinal function. Enteral nutrition has been widely used in clinical practice because of its physiological and cost-effective advantages. Nasointestinal tube is an important means of establishing enteral nutrition access for adult patients. It is commonly used in patients with high risk of aspiration dysphagia dysphagia and severe traumatic brain injury after gastrectomy. Parenteral nutrition through the nasointestinal tube has the advantages of safety and fewer complications. Many clinical trials have also confirmed that the establishment of nutritional route through the nasointestinal tube is very safe and effective. Enteral nutrition via nasointestinal tube not only helps the patient's bowel movement and provides the nutrients needed by the body but also rapidly establishes an enteral nutrition route to increase the patient􀆳s energy intake thereby improving the prognosis. Recently the Nutritional Access Group of Chinese Society for Oncological Nutrition and Supportive Care released the Guidelines for Nutritional access for Adult Patients in China. The article summarizes the evidence and interprets the recommendations in the nasointestinal section of the guideline.