Strategy of perioperative nutrition therapy for pancreatic cancer

Zheng Xin, Sun Bei

Electronic Journal of Metabolism and Nutrition of Cancer ›› 2023, Vol. 10 ›› Issue (6) : 705-710.

PDF(926 KB)
PDF(926 KB)
Electronic Journal of Metabolism and Nutrition of Cancer ›› 2023, Vol. 10 ›› Issue (6) : 705-710.

Strategy of perioperative nutrition therapy for pancreatic cancer

  • Zheng Xin, Sun Bei
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Abstract

Patients with pancreatic cancer are susceptible to perioperative malnutrition. Preoperative malnutrition factors include pancreatic insufficiency and tumor-induced metabolic changes postoperative stress and inflammation increase the risk of short-term nutritional deterioration and perioperative malnutrition is an independent risk factor for overall poor prognosis so it is necessary to carry out a comprehensive nutritional management. Nutritional screening is routinely performed after admission and quantitative nutritional screening tools can be used to determine the nutritional risk. Further nutritional assessment is required for patients with higher nutritional risk. Enhanced recovery after surgery suggests that nutritional therapy should be performed for patients who have lost more than 15% of their body weight or have a body mass index of less than 18. 5 kg / m 2 before surgery and nutritional therapy should be based on the principle of stepwise escalation. The preoperative nutritional status will affect the timing of surgery. A single indicator cannot completely describe the nutritional status of postoperative patients and it is recommended to use multiple methods to dynamically monitor the nutritional status and analyze it comprehensively. Postoperative nutritional therapy should be individualized in accordance with the patient 's condition and nutritional status and a reasonable choice of nutritional support pathway can avoid additional pain and economic burden for patients. Early oral feeding is considered to be safe and effective but artificial nutrition should be initiated in time for patients with poor oral tolerance. Enteral nutrition has advantages such as maintaining intestinal function but total parenteral nutrition is of great value in the treatment of severe intestinal fistula delayed gastric emptying and other complications.

Key words

Pancreatic cancer / Perioperative period / Nutritional therapy / Pancreatic exocrine insufficiency / Enhanced recovery after surgery

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Zheng Xin, Sun Bei. Strategy of perioperative nutrition therapy for pancreatic cancer[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2023, 10(6): 705-710
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