The incidence of malnutrition in hospitalized patients is high and proper nutritional treatment can improve the nutritional status of patients reduce stress damage reduce the incidence of complications and mortality and thus accelerate the recovery of patients. As an indispensable and important part of the course of disease treatment clinical nutrition has been paid more and more attention. Establishing a standardized clinical nutrition diagnosis and treatment path to improve patients' nutritional status and clinical outcomes is the key problem in the medical field. In April 2023 Guideline for clinical application of parenteral and enteral nutrition in adults patients in China 2023 edition was officially published. Based on published clinical nutrition guidelines and the latest clinical evidence at home and abroad the guidelines propose 60 recommendations from 37 specific issues such as nutrition screening and assessment enteral nutrition and parenteral nutrition clinical practice. It comprehensively summarizes the clinical diagnosis and treatment principles which also provides more comprehensive nutritional treatment program guidance. This article will interpret some key contents of the guideline to provide a clinical reference for the standardized nutritional diagnosis treatment and management of patients.