Chronic inability or lack of oral food can lead to malnutrition requiring parenteral nutrition treatment. Patients who need long- term parenteral nutritional therapy can implement home parenteral nutritional therapy at home under the guidance of a professional nutritional support team in order to maintain and improve the nutritional status of the patient and avoid long - term hospitalization save medical costs and improve the quality of life. In 2023 the ESPEN guidelines on home parenteral nutrition. It builds on previously published guidance provides an update on the available evidence and expert opinion and visualizes the recommendations by presenting them as a flowchart. It unified 71 recommendations of home parenteral nutrition central venous access device CVAD including central venous catheter peripherally inserted central catheter and implantable venous access port and infusion pump infusion catheter and CVAD site care nutritional preparations program monitoring and management. These recommendations have great value in guiding home parenteral nutritional management of patients. We interpret the guidelines and reorganize the recommendations to improve the understanding and practicability.