Patients who are at high nutritional risk or are malnourished whose nutritional needs are not met by oral pathways and whose gastrointestinal function is normal should be treated with enteral nutrition therapy. If the patient's nutritional intake is likely to be qualitatively or quantitatively inadequate for a week or more enteral nutrition support therapy may be administered at home under the guidance of a professional nutrition support team. The implementation of home enteral nutrition can effectively reduce the incidence of complications and hospital stay save medical costs improve the clinical outcome of patients and have significant clinical and cost effectiveness. With the development of medical treatment more patients are willing to receive long-term enteral nutrition support at home. In 2022 the European Society for Clinical Nutrition and Metabolism ESPEN published the latest edition of the practical guideline Home enteral nutrition which build on the guidelines published in 2019 providing the latest available evidence and expert opinion and the content is presented in the form of a decision flow chart to make it more intuitive and refined. The guidelines put forward 61 recommendations on 5 aspects indications for HEN equipment evaluation for HEN recommended products for HEN monitoring and termination of HEN and structural requirements for HEN providing very important reference opinions for guiding patients to conduct home enteral nutrition therapy. This article interprets the guidelines recategorize recommendations and aims to improve understanding and provide guidance for family enteral nutrition practice.