生物电阻抗法测定体成分在肿瘤患者中的应用

闫超,王丹丹,杜红珍,谢颖,骆彬,李增宁

肿瘤代谢与营养电子杂志 ›› 2019, Vol. 6 ›› Issue (1) : 104-109.

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肿瘤代谢与营养电子杂志 ›› 2019, Vol. 6 ›› Issue (1) : 104-109. DOI: 10.16689/j.cnki.cn11-9349/r.2019.01.020
综述

生物电阻抗法测定体成分在肿瘤患者中的应用

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Application of bioelectrical impedance analysis to measure body composition in cancer patients

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摘要

生物电阻抗分析法是一种非侵入性并用于评估人体成分和营养状况的方法,可以有效地追踪人体成分随时间的 变化。肿瘤患者由于受肿瘤类型、位置、分期和治疗途径的影响,其营养不良的发生率不同。营养不良是肿瘤患者常见的 症状,增加了死亡率和治疗并发症,降低了治疗效果和生活质量。肿瘤患者通常有发生恶病质的风险,这与进行性体重减轻, 肌肉和脂肪组织丢失,免疫功能受损以及由食物摄入减少,全身炎症和异常代谢的可变组合引起的代谢紊乱有关。生物电 阻抗分析法能够定性、定量分析体内不同组织的构成,准确反映机体组分的改变,是评价肿瘤患者营养状况的良好工具。 研究表明,生物电阻抗分析法和相位角测量的应用使肿瘤患者在预防、诊断和预后多方位的临床管理中受益。通过生物电 阻抗分析法获得的相位角和去脂体重已被用作肿瘤患者营养状态和存活率的预测因子。本综述旨在总结有关生物电阻抗法 测定肿瘤患者人体成分的现有文献,从而更好地为临床营养监测和营养支持提供依据。

Abstract

 Bioelectrical impedance analysis is non-invasive, validated method to assess body composition and nutritional status, which offers an efficacious way to track changes in body composition over time. Cancer patients have different rates of malnutrition due to the type, location, stage, and treatment route of the tumor. Malnutrition is commonly reported in cancer patients and can increase mortality and treatment complications, and can reduce treatment effectiveness and quality of life. Cancer patients are usually at risk of developing cachexia, which is associated with progressive weight loss, loss of muscle and fat tissue, impaired immune function, and metabolic disturbances caused by a variable combination of reduced food intake, systemic inflammation and abnormal metabolism. The bioelectrical impedance analysis method can qualitatively and quantitatively analyze the composition of different tissues in the body and accurately reflect the changes of the components of the body. It is a good tool for evaluating the nutritional status of cancer patients. Studies indicate that the use of bioelectrical impedance analysis and phase angle measures can benefit in the clinical management of cancer patients in multiple ways: in the prevention, diagnosis and prognosis. The phase angle and fatfree mass obtained by bioelectrical impedance analysis has been used as a predictor of nutritional status and survival rate in cancer patients. This systematic review sought to summarise current literature surrounding body composition assessment in cancer patients to provide a basis for clinical nutrition monitoring and nutritional support.

关键词

肿瘤 / 生物电阻抗 / 人体成分分析 / 相位角 / 营养不良

Key words

 Cancer / Bioelectrical impedance analysis / Body composition / Phase angle / Malnutrition

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导出引用
闫超,王丹丹,杜红珍,谢颖,骆彬,李增宁. 生物电阻抗法测定体成分在肿瘤患者中的应用[J]. 肿瘤代谢与营养电子杂志. 2019, 6(1): 104-109 https://doi.org/10.16689/j.cnki.cn11-9349/r.2019.01.020
YAN Chao,WANG Dan-dan, DU Hong-zhen, XIE Ying, LUO Bin, LI Zeng-ning. Application of bioelectrical impedance analysis to measure body composition in cancer patients[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2019, 6(1): 104-109 https://doi.org/10.16689/j.cnki.cn11-9349/r.2019.01.020

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