摘要
目的 探究胃肠道肿瘤患者的营养状况，并分析患者的营养状况对术后感染的影响。方法 收集2016年1月至2019年3月重庆医科大学附属永川医院行肿瘤手术治疗的271例胃肠道肿瘤患者的相关资料，运用营养风险筛查2002（NRS 2002）在患者术前进行营养风险筛查，根据筛查结果分为有营养风险组（121例）与无营养风险组（150例），比较两组患者一般观察指标以及术后感染、入住重症监护病房之间的差异，并分析患者术后感染的发生与术前营养状况、年龄、术前血液学指标、手术情况、肿瘤情况等多因素的相关性。结果 胃肠道肿瘤患者术前营养风险的发生率为44.6%，有营养风险组的术前总蛋白、白蛋白、血红蛋白以及淋巴细胞总数均低于无营养风险组，且差异有统计学意义（P<0.05）；术后有营养风险组感染发生率为27.3%（33/121），无营养风险组术后感染发生率为14.7%（22/150），两组差异有统计学意义。多因素Logistic回归分析显示术后感染的危险因素与NRS 2002 ≥ 3分、饮酒史、手术时长 ≥ 6h相关，差异有统计学意义（P<0.05）。结论 胃肠道肿瘤患者术前营养风险的发生率高，NRS 2002评分低的患者术后感染发生率较高，应该积极采取措施改善患者的营养状况。
Abstract
Objective To explore the nutritional status of patients with gastrointestinal cancer and analyze the impact of the nutritional status of patients on postoperative infections， and to provide evidence for prevention and control of postoperative infection. Methods The relevant data of 271 patients with gastrointestinal cancer who underwent tumor surgery Yongchuan Hospital Affiliated to Chongqing Medical University from January 2016 to March 2019 were collected， the nutritional risk screening tool （NRS 2002） was used to screen the nutritional risk of patients before operation， according to the screening results， they were divided into nutrition risk group （121 cases） and non-nutrition risk group（150 cases），the differences between the two groups in general observation indexes， postoperative infection and admission to ICU were compared， and the correlation between the occurrence of postoperative infection and preoperative nutritional status， age， preoperative hematology indexes， surgical status， tumor status and other factors was analyzed. Results The preoperative nutritional risk of patients with gastrointestinal cancer was 44.6%，the total protein， albumin， hemoglobin and lymphocyte in the nutrition risk group were lower than those in the non-nutrition risk group， and the difference were statistically significant （P<0.05）；the incidence of postoperative infection was 27.3% （33/121） in the nutrition risk group and 14.7% （22/150） in the non-nutrition risk group， the difference between the two groups was statistically significant. Multivariate Logistic regression analysis showed that the risk factors of postoperative infection were associated with NRS 2002 ≥ 3 points， drinking history， and operation duration ≥6h， and the differences were statistically significant （P<0.05）. Conclusion The incidence of preoperative nutritional risk in patients with gastrointestinal cancer is high， the incidence of postoperative infection is high in patients with low NRS 2002 score， active measures should be taken to improve the nutritional status of patients.
关键词
胃肠道肿瘤 /
营养状况 /
术后感染
Key words
Gastrointestinal cancer /
Nutritional status /
Postoperative infection
刘祖平，白鍊，曾永红，唐英，吕运利，陈小玉.
胃肠道肿瘤患者的营养状况与术后感染情况的分析[J]. 肿瘤代谢与营养电子杂志. 2020, 7(2): 183-187 https://doi.org/10.16689/j.cnki.cn11-9349/r.2020.02.009
Liu Zuping， Bai Lian，Zeng Yonghong，Tang Ying，Lyu Yunli，Chen Xiaoyu.
Analysis of nutritional status and postoperative infection in patients with gastrointestinal cancer[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2020, 7(2): 183-187 https://doi.org/10.16689/j.cnki.cn11-9349/r.2020.02.009
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