目的 观察肿瘤患者生活方式全程医学管理(MCL)对多肿瘤术后康复效果的影响。方法 选取 50 例实体瘤患者, 随机分为干预组、对照组,25 例干预组患者围术期接受MCL 管理,25 例疾病诊疗背景相同的肿瘤患者作常规处理,比较两 组患者住院时间、术后并发症、营养风险筛查、营养评估、主要实验室指标、生活质量等的差异。结果 50 例患者全部按计 划完成肿瘤手术治疗。干预组和对照组住院时间、术后并发症、营养评估、KPS 评分差异有统计学意义(P<0.05)。与对 照组比较,干预组血清总蛋白、白蛋白、前白蛋白有显著差异(P<0.05),白细胞、淋巴细胞、血红蛋白、血小板无显著 差异。干预组患者情绪功能、恶心与呕吐、食欲低下、失眠及腹泻显著改善(P<0.05)。PG-SGA 评分与总蛋白、白蛋白、 前白蛋白水平具有相关性(P<0.05)。结论 MCL 可缩短肿瘤患者手术住院时间,减少术后并发症,改善营养状况,提升 血清总蛋白、白蛋白、前白蛋白水平,同时改善患者情绪功能,减轻恶心与呕吐、食欲低下、失眠及腹泻症状。
Objective To explore the effect of Medical Supervision For Cancer (Chronic Disease) Patients' Healthy Lifestyle (MCL) on the postoperative rehabilitation of tumor patients. Methods Fifty patients with solid tumor were randomly assigned into the intervention group or the control group. Twenty-five patients in the intervention group were given MCL during perioperative period, while another 25 cancer patients with the same disease background were subjected to routine clinical treatments. Hospital stay, postoperative complications, nutritional risk screening, nutritional assessment, main laboratory values and quality of life of 2 groups were compared. Results All 50 patients completed the operation as planned. The differences in hospital stay, postoperative complication incidence rate, nutritional assessment and KPS score were statistically significant between 2 groups (P<0.05). The values of leukocyte, lymphocyte, hemoglobin, platelet of 2 groups have no statistically significant difference (P>0.05). The emotional function, nausea and vomiting, loss of appetite, insomnia and diarrhea in the intervention group were significantly improved compared with the control group (P<0.05). PG-SGA score is correlated with total protein, prealbumin and albumin levels (P<0.05). Conclusions MCL can shorten the hospital stay, reduce the incidence of postoperative complications, improve nutritional status, enhance serum total protein, prealbumin and albumin levels, improve emotional function, reduce the incidence of nausea and vomiting, appetite loss, insomnia and diarrhea.