膳食纤维的抗炎作用

陈会永;黄河

肿瘤代谢与营养电子杂志 ›› 2015, Vol. 2 ›› Issue (4) : 63-68.

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肿瘤代谢与营养电子杂志 ›› 2015, Vol. 2 ›› Issue (4) : 63-68.
综述

膳食纤维的抗炎作用

  • 陈会永,黄河
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Anti-inflammatory effects of dietary fiber

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摘要

摘要:目的 总结膳食纤维的定义及其生理功能,归纳其抗炎作用的机制。 方法 回顾近年来国内外发表的涉及膳食纤 维定义、生理功能及其抗炎作用的中、英文文献。 结果 膳食纤维是不能被人体小肠消化、吸收的,由多种单体成分所形成 的糖类聚合物。膳食纤维分为可溶性膳食纤维和不可溶性膳食纤维,其中可溶性膳食纤维能被肠道菌群代谢分解为短链脂 肪酸。膳食纤维或短链脂肪酸通过影响机体炎症细胞的分化、炎症因子的表达、肠道菌群及肠黏膜屏障的功能,从而预防 炎症的发生。 结论 膳食纤维具有一定的抗炎作用,但其具体机制尚需进一步研究。

Abstract

Abstract: Objective To summarize the definition and physiological function of dietary fiber and to conclude the mechanism of anti-inflammatory effect. Methods We review the role of dietary fiber definition, physiological function and the mechanism of antiinflammatory effect in the domestic and foreign published literature in recent years. Results Dietary fiber is a kind of carbohydrate polymers, which is composed of a variety of monomer component and can't be digested or absorbed by small intestinal. It could be classified into soluble dietary fiber and insoluble dietary fiber, of which the former one can be decomposed into short chain fatty acids by gut flora metabolism. Many recent studies have shown that dietary fiber or short chain fatty acids exerts a preventive effect on inflammation by affecting differentiation of inflammatory cells, expression of inflammatory cytokines, intestinal flora and intestinal mucosal barrier function. Conclusions Dietary fiber has certain function of anti-inflammatory, but much research is needed to explore the mechanism of the anti-inflammatory effect of dietary fiber.

关键词

膳食纤维 / 抗炎

Key words

Dietary fiber / Anti-inflammatory

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陈会永;黄河. 膳食纤维的抗炎作用[J]. 肿瘤代谢与营养电子杂志. 2015, 2(4): 63-68
Anti-inflammatory effects of dietary fiber[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2015, 2(4): 63-68

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