摘要：目的 比较分析进展期胃癌患者血清 PA 水平和 PG-SGA 评分之间的关系，探讨更为科学的进展期胃癌患者营养 评估方法。方法 选取山西省人民医院普外科 2015 年 5 月 1 日至 2016 年 5 月 1 日期间收治的可根治性切除进展期胃癌患者 72 例，运用 PG-SGA 量表进行营养评估，同时测定空腹静脉血清 PA 水平，采用 Spearman 相关系数法分析 PA 水平与 PG- SGA 评分之间的相关性。结果 72 例进展期胃癌患者中，营养不良（PG-SGA ≥ 4 分）患者 48 例，占 67%；营养不良患者 PA 平均水平为 152.57±46.95mg/L，明显低于非营养不良患者的 252.68±44.31mg/L（P ＜ 0.001）；PA 水平越高，PG-SGA 分值越低。PG-SGA 评分≥ 4 分的 PA 临界值为 186.82 mg/L（P ＜ 0.001）。结论 进展期胃癌患者有较高的营养不良发生 率；其 PA 水平与 PG-SGA 评分存在负相关关系，当 PA 水平低于 186.82mg/L 时，患者存在营养不良（PG-SGA ≥ 4 分）。 PA 水平测定和 PG-SGA 评分相结合可更准确地评估进展期胃癌患者营养状况。

Abstract: Objective To probe a more scientific nutritional assessment tool for patients with advanced gastric carcinoma by comparing and analyzing the relationship between PA levels and PG-SGA score. Methods 72 patients with advanced gastric carcinoma and suitable for radical resection were enrolled in this study by the Department of General Surgery in Shanxi People's Hospital from May 1, 2015 to May 1, 2016. PG-SGA was applied for nutritional status evaluation, venous serum PA levels was measured for protein level, and the Spearman correlation coefficient method was used to analyze the correlation between PA levels and PG-SGA score. Results Among the 72 advanced gastric carcinoma patients, 48 cases (67%) were in malnutrition (PG-SGA≥4) with a PA levels at 152.57±46.95mg/L, significantly lower than the non-malnutrition group (252.68±44.31mg/L, P<0.001); The higher PA levels was, the lower PG-SGA score got, the cut-point PA levels was 186.82mg/L when the PG-SGA score was equal/ higher than 4 points (P<0.001). Conclusions The incidence of malnutrition in patients with advanced gastric carcinoma was high; the results of this study confirmed that PA levels and PG-SGA score had a negative correlation, when the PA levels was lower than 186.82mg/L, the patients were malnourished. The combination of PA levels and PG-SGA score could provide comprehensive assessment of the nutritional status for patients with advanced gastric carcinoma.