目的 观察术前口服免疫营养治疗在伴营养风险的食管癌患者恢复中的临床效果。方法 纳入 2016年 6月至 2019年6月在东南大学附属江阴市人民医院胸外科行手术治疗的食管癌患者80例，按照随机数字表法随机分为试验组及对照 组，对照组采取常规术前准备，试验组予以术前口服免疫营养治疗。比较两组间的血液营养免疫数据及临床结局。结果 两组 患者的一般资料、入院检测的各项营养免疫指标、手术方式和pTNM分期数据相比，差异无统计学意义（P>0.05）；试验组患者 术前1 d和术后1 d的白蛋白、前白蛋白指标高于观察组，两者差异有统计学意义（P<0.05）；试验组患者术前1 d、术后1 d和术 后7 d的淋巴细胞计数指标高于观察组，两者差异有统计学意义（P<0.05）；两组间术后7 d的白蛋白、前白蛋白指标相比不具有 统计学意义（P>0.05）；两组患者的术后肠内营养不良反应发生率、肛门排气时间、住院时间和住院费用指标相比具有统计学意 义（P<0.05）；两组并发症发生率差异无统计学意义（P>0.05）。结论 术前口服免疫营养治疗能够改善伴营养风险的食管癌患 者围手术期的营养状况，促进术后早期恢复，可作为伴营养风险的食管癌患者的一种术前营养治疗手段。

Objectives To investigate the effect of preoperative oral immunonutrition in the recovery of patients with esophageal cancer with nutritional risk. Methods A total of 80 cases of esophageal cancer patients treated in our hospital from March 2014 to March 2017 were divided randomly into the experimental group or the control group. The clinical data were compared between the two groups. Results No difference were observed between the two groups with respect to general data, surgical methods, pTNM staging data, complication rate, albumin and prealbumin indexes 7 days after surgery（P>0.05）. However, compared with control group, a significant decrease occurred in albumin, prealbumin, lymphocyte counts before and 1 day after surgery and lymphocyte counts 7 days after surgery and the incidence of intestinal adverse reactions, anal exhaust time, hospitalization day, hospitalization expense in the experimental group（P<0.05）. Conclusions Preoperative oral immunonutrition can improve the perioperative nutritional status of patients with esophageal cancer with nutritional risk and promote early postoperative recovery. It can be used as a preoperative support for these patients.