目的 探讨体质指数（BMI）对胶质瘤患者术后颅内感染发生的预测价值，为胶质瘤患者诊疗方案提供营养参 考。方法 回顾性队列研究调查并收集就诊于宁夏医科大学附属医院神经外科 2016年 1月至 2018年 12月行胶质瘤切除术 患者临床资料共 128例，根据患者术后颅内感染发生情况将患者分为颅内感染组与对照组并分析两组患者一般情况、手术 重要事件、术后主要结局指标差异性，单因素分析采用卡方检验，多因素分析采用 Logistic 回归分析，分析胶质瘤术后颅内 感染发生的独立危险因素。结果 术后颅内感染患者共33例，累计感染率为25.78%；其中BMI<18.5 kg/m2（63.64%），18.5 kg/m2< BMI<25.9 kg/m2(18.56%)，BMI>26 kg/m2（38.10%）。单因素分析显示患者糖尿病史、术中失血˃300 ml、手术时长˃4 h 及 BMI< 18.5 kg/m2或BMI>26 kg/m2 与术后颅内感染发生差异具有统计学意义（P<0.05）。多因素分析显示手术时长>4 h和BMI<18.5 kg/m2 或BMI>26 kg/m2 是胶质瘤患者术后发生颅内感染的独立危险因素（P<0.05）。结论 手术时长>4 h是患者术后发生颅内感染的独 立危险因素，对胶质瘤患者术后颅内感染发生具有一定预测价值，同时当患者术前BMI<18.5 kg/m2或BMI>26 kg/m2 时应给予其更 多关注以预防其术后颅内感染的发生。

Objective To explore the predictive value of body mass index (BMI) for the occurrence of intracranial infection in patients with glioma, and to provide a reference of the diagnosis and treatment for patients with glioma. Methods To investigate and collect the clinical data of 128 patients who underwent glioma resection from January 2016 to December 2018 in the Department of Neurosurgery, General Hospital of Ningxia Medical University. The patients were divided into intracranial infection group and control group based on the incidence of postoperative intracranial infection. The differences in general conditions, important surgical events, and main postoperative outcome indicators between the two groups of patients were analyzed, and the independent risk factors for intracranial infection after glioma were analyzed. Chi-square test or Logistics regression analysis. Results There were 33 patients with postoperative intracranial infection, and the cumulative infection rate was 25.78%. Among them, BMI<18.5 kg/m2 (63.64%), 18.5 kg/m2 <25.9 kg/m2 (18.56%), BMI>26 kg/m2（38.10%）. Univariate analysis showed that the history of diabetes, intraoperative blood loss more than 300 ml, operation time more than 4 h, and BMI<18.5 kg/m2 or BMI>26 kg/m2 were associated with the occurrence of postoperative intracranial infection (P<0.05). Multivariate analysis showed that operation time more than 4 h and BMI<18.5 kg/m2 or BMI>26 kg/m2 were independently associated with intracranial infection in patients with glioma (P<0.05). Conclusion BMI has a certain predictive value for the occurrence of postoperative intracranial infection in patients with glioma. When the patient with BMI<18.5 kg/m2 or BMI>26 kg/m2, more attention should be given to prevent the occurrence of postoperative intracranial infection.