不同营养治疗对肺癌术后乳糜胸的临床结局对比分析

1,2刘 欢,1,3胡 雯,3程 懿,4赵义熙

肿瘤代谢与营养电子杂志 ›› 2021, Vol. 8 ›› Issue (4) : 420-423.

肿瘤代谢与营养电子杂志 ›› 2021, Vol. 8 ›› Issue (4) : 420-423.
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不同营养治疗对肺癌术后乳糜胸的临床结局对比分析

  • 1,2刘 欢,1,3胡 雯,3程 懿,4赵义熙
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Clinical outcomes of the postoperative lung cancer with chylothorax receiving different nutritional treatments: a comparative study

  • 1,2LiuHuan,1,3HuWen,3ChengYi,4ZhaoYixi
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摘要

目的 探讨3种不同营养治疗对肺癌术后乳糜胸患者的临床结局。方法 将入选的45例患者随机分为三组:全肠外 营养(TPN)组、中链甘油三酯饮食(MCT)组和低脂饮食(LF)组,每组各15例。患者确诊乳糜胸后进行相应营养治疗。分析三组 患者的白蛋白水平、胸腔引流量、主观舒适度、拔管时间及营养费用等指标。结果 三组患者诊断乳糜胸时白蛋白水平均较入院 时显著下降(P<0.05),经过营养治疗后,三组患者出院时白蛋白水平均较诊断时明显升高,差异有统计学意义(P<0.05); 营养治 疗第7天时三组患者主观舒适度评分均较诊断乳糜胸时降低(P<0.05),其中,TPN组主观舒适度评分最高,其次是LF组,最后是 MCT组。两两比较差异均有统计学意义(P<0.05);营养治疗7 d后三组胸腔引流量、拔管时间和结扎手术率差异均无统计学意义 (P>0.05),但MCT组和LF组营养治疗费用和诊断后住院时间均显著短于TPN组(P<0.05)。结论 肺癌术后乳糜胸患者应首选 添加MCT饮食作为营养治疗方式。

Abstract

Objective To observe the clinical outcomes of three different nutritional treatments for the postoperative lung cancer with chylothorax patients, and to provide reference for future clinical treatment. Methods According to the inclusion and exclusion criteria, 45 patients were randomly divided into 3 groups: total parenteral nutrition (TPN) group, medium⁃chain triglyceride (MCT) diet group and low⁃fat (LF) diet group, with 15 patients in each group. After diagnosis of chylothorax, the patient immediately received nutritional treatment. Results Albumin levels of patients in the three groups were significantly lower at the time of diagnosis of chylothorax than at the time of admission (P<0.05). After nutritional treatment, albumin levels of patients in the three groups were significantly higher at the time of discharge than at the time of diagnosis, and the difference was statistically significant (P<0.05). The subjective comfort scores after 7 days nutritional treatment of the three groups were lower than that at the time of diagnosis of chylothorax (P<0.05), and the subjective comfort score of the TPN group was highest, followed by the LF group and TPN group in turn, with obvious difference between mutual groups (P<0.05). The amount of chest drainage after 7 days of nutritional treatment, the time to removal of drainage tube and ligation rate were no significant in the three groups (P>0.05).But the cost of nutritional treatment and the length of hospital stay after diagnosis in the MCT group and LF group were significantly lower than those in the TPN group (P<0.05). Conclusion The diet supplemented with MCT should be the first choice of nutritional treatment for the postoperative lung cancer with chylothorax patients.

关键词

肺癌 / 乳糜胸 / 营养治疗

Key words

Lung cancer / Chylothorax / Nutritional treatment

引用本文

导出引用
1,2刘 欢,1,3胡 雯,3程 懿,4赵义熙. 不同营养治疗对肺癌术后乳糜胸的临床结局对比分析[J]. 肿瘤代谢与营养电子杂志. 2021, 8(4): 420-423
1,2LiuHuan,1,3HuWen,3ChengYi,4ZhaoYixi. Clinical outcomes of the postoperative lung cancer with chylothorax receiving different nutritional treatments: a comparative study[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2021, 8(4): 420-423

基金

四川省科技计划项目(2019YJ0042)

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