预后营养指数和NRS 2002评分对肺癌患者预后的临床 研究

1程 兰,1许庆珍,1李从玲,2李 李,1解明然,3李 毅

肿瘤代谢与营养电子杂志 ›› 2021, Vol. 8 ›› Issue (5) : 534-538.

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肿瘤代谢与营养电子杂志 ›› 2021, Vol. 8 ›› Issue (5) : 534-538.
论著

预后营养指数和NRS 2002评分对肺癌患者预后的临床 研究

  • 1程 兰,1许庆珍,1李从玲,2李 李,1解明然,3李 毅
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A clinical study on prognosis of lung cancer patients by prognostic nutritional index and NRS 2002 scores

  • 1ChengLan,1XuQingzhen,1LiCongling,2LiLi,1XieMingran,3LiYi
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摘要

目的 运用预后营养指数(PNI)和营养风险筛查2002(NRS 2002)评估筛查肺癌患者术前的营养状况,比较其对预后的 影响。方法 收集中国科学技术大学附属第一医院(安徽省立医院)胸外科2017年1月至10月确诊肺癌患者172例,采用PNI和 NRS 2002评估肺癌患者术前的营养状况。以PNI 48为截点分为高PNI组与低PNI组;NRS 2002评分≥3分者存在营养风险,<3分 者为无营养风险。结果 低PNI组淋巴结转移例数、TNM分期较晚比例及术后并发症发生率高于高PNI组,且术后住院时间和拔 胸引管时间长于高PNI者(P<0.05);营养风险发生率为16.86%, 有营养风险组的TNM分期较晚、术后辅助治疗比例及术后并发 症发生率高于无营养风险者,且拔胸引管时间长于无营养风险组(P<0.05)。在预测肺癌术后并发症方面,PNI的特异度高于NRS 2002评分(85.5%比67.5%,P>0.05)。结论 术前营养状况在一定程度上影响肺癌患者预后;两种评价方法在预测肺癌患者的术 后并发症方面无明显差异,但PNI 的特异性更高。鉴于两个评价方法获得简单方便,具有一定的临床应用价值。

Abstract

Object To evaluate the preoperative nutritional status of patients with lung cancer surgery by PNI and NRS 2002, and to compare their effects on prognosis. Methods A total of 172 patients with lung cancer diagnosed from January 2017 to October 2017 in the Department of Thoracic Surgery, Anhui Provincial Hospital, the First Affiliated Hospital of China University of Science and Technology were enrolled. The prognostic nutrition index (PNI) and nutritional risk screening 2002 (NRS 2002) were used to evaluation the preoperative nutritional status of lung cancer patients.The patients were divided into high PNI group and low PNI group with a cutoff point of 48. Nutritional risk screening was performed at admission. Patients with a NRS 2002 total score of ≥3 had a nutritional risk, and those with a score of <3 had no nutritional risk. Results The number of lymph node metastasis,late TNM stage and postoperative complication rates in the low PNI group were higher than in the high PNI group,and the postoperative hospital stay and chest lead time were longer than those in the high PNI group(P<0.05). The incidence of nutritional risk was 16.86%. The late TNM stage,postoperative adjuvant treatment and postoperative complication rates in the nutrition risk group were higher than in the no nutrition risk group,and chest lead time was longer than that in the no nutrition risk group(P<0.05). In terms of specificity of the two nutritional assessment methods in predicting postoperative complications of lung cancer, PNI was higher than NRS 2002 score(85.5% vs 67.5%,P>0.05). Conclusion The preoperative nutritional status can affect the prognosis of lung cancer patients to some extent. There was no significant difference in predicting the postoperative complications of lung cancer patients, the specificity of PNI was higher than that of NRS 2002. In view of the simplicity and convenience of the two evaluation methods, it has certain clinical application value.

关键词

预后营养指数 / 营养风险筛查2002 / 肺癌 / 预后

Key words

Prognostic nutritional index / Nutritional risk screening 2002 / Lung cancer / Prognosis

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导出引用
1程 兰,1许庆珍,1李从玲,2李 李,1解明然,3李 毅. 预后营养指数和NRS 2002评分对肺癌患者预后的临床 研究[J]. 肿瘤代谢与营养电子杂志. 2021, 8(5): 534-538
1ChengLan,1XuQingzhen,1LiCongling,2LiLi,1XieMingran,3LiYi. A clinical study on prognosis of lung cancer patients by prognostic nutritional index and NRS 2002 scores[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2021, 8(5): 534-538

基金

国家自然科学基金(81973643) 安徽省重点研究与开发项目(202004j07020017)

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