常见恶性肿瘤住院患者营养状况及影响因素分析

1翁敏,1代正燕,1甘志明,1杨柳青,2,3石汉平,4王昆华

肿瘤代谢与营养电子杂志 ›› 2022, Vol. 9 ›› Issue (2) : 195-199.

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肿瘤代谢与营养电子杂志 ›› 2022, Vol. 9 ›› Issue (2) : 195-199.
论著

常见恶性肿瘤住院患者营养状况及影响因素分析

  • 1翁敏,1代正燕,1甘志明,1杨柳青,2,3石汉平,4王昆华
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Analysis of nutritional status and influencing factors of hospitalized patients with common cancer

  • 1Weng Min, 1Dai Zhengyan, 1Gan Zhiming, 1Yang Liuqing, 2,3Shi Hanping, 4Wang Kunhua
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摘要

目的研究常见恶性肿瘤住院患者的营养状况及其影响因素。方法选取2018年1月至2019年12月昆明医科大学第 一附属医院病理确诊为恶性肿瘤的1385例患者,记录患者人口学资料,进行人体学测量,并收集患者入院48 h内的生化检验结 果,同时采用患者主观整体评估量表(PG‐SGA)进行营养状况评估,并分析营养状况的影响因素。结果1385例恶性肿瘤患者,其 中男性980例(70.8%),女性405例(29.2%),平均年龄为(56.5±13.4)岁。PG‐SGA评分为(6.92±5.27)分,营养良好、可疑/轻度营 养不良、中度营养不良、重度营养不良发生比例分别为14.7%(203/1385)、20.1%(279/1385)、31.0%(429/1385)、34.2%(474/1385)。 患者在住院期间仅23.0%(319/1385)使用过肠内营养,36.6%(507/1385)使用过肠外营养,同时使用肠内和肠外营养的比例为7.1% (99/1385)。控制相关混杂因素后,多因素Logistic回归分析显示年龄(≥70岁)、男性、肿瘤有转移、近1~3个月体重下降及近1周 饮食下降是营养不良发生的危险因素,较高的血清白蛋白、血红蛋白及握力是营养不良的保护因素,差异有统计学意义(P<0.05)。 结论恶性肿瘤住院患者营养不良的发生比例高达85.3%,中重度营养不良高达65.2%,但营养治疗率低。年龄(≥70岁)、男性、肿 瘤有转移、近1~3个月体重有下降及近1周饮食有下降的患者更容易发生营养不良,血清白蛋白、血红蛋白及握力水平高的患者 不容易发生营养不良。

Abstract

Objective To investigate the nutritional status of hospitalized patients with common cancer and influencing factors. Method From January 2018 to December 2019, we enrolled 1385 patients with cancer hospitalized for treatment in First Affiliated Hospital of Kunming Medical University. These patients were diagnosed with malignant tumors by pathologically. Demographic data, anthropometric measurements and laboratory examination within 48 hours of admission were collected, patient⁃generated subjective global assessment (PG⁃SGA) was used to evaluate the nutritional status and influencing factors of nutritional status were analyzed. Result There are 980 males (70.8%) and 405 females (29.2%), and average age of (56.5±13.4) years in our 1385 cases. The average PG⁃SGA score was (6.92±5.27), with PG⁃SGA score as standard, 203 patients (14.7%) had the good nutrition, 279 patients (20.1%) were mild malnutrition, 429 patients (31.0%) were moderate malnutrition, 474 patients (34.2%) were severe malnutrition. 23.0% (319/ 1385) of patients received enteral nutritional therapy, 36.6% (507/1385) received parenteral nutritional therapy, 7.1% (99/1385) received enteral and parenteral nutritional therapy. After controlling for confounding factors, Logistic regression analysis demonstrates that age (≥70 years old), male, tumor metastasis, weight loss in the recent 1-3 months and diet loss in the recent 1 week were risk factors for malnutrition. Higher serum albumin, hemoglobin and hand grip strength were protective factors for malnutrition, the differences were statistically significant (P<0.05). Conclusion With PG⁃SGA score as standard, 85.3% of the cancer patients were malnutrition and 65.2% of them were moderate/severe malnutrition, and there was a low rate of nutritional treatment. Patients with age (≥70 years old), male, tumor metastasis, weight loss in the recent 1⁃3 months and diet loss in the recent 1 week are likely to have malnutrition. Patients with higher serum albumin, hemoglobin and hand grip strength have less malnutrition.

关键词

恶性肿瘤 / 营养不良 / 影响因素

Key words

Cancer / Malnutrition / Influencing factors

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导出引用
1翁敏,1代正燕,1甘志明,1杨柳青,2,3石汉平,4王昆华. 常见恶性肿瘤住院患者营养状况及影响因素分析[J]. 肿瘤代谢与营养电子杂志. 2022, 9(2): 195-199
1Weng Min, 1Dai Zhengyan, 1Gan Zhiming, 1Yang Liuqing, 2,3Shi Hanping, 4Wang Kunhua. Analysis of nutritional status and influencing factors of hospitalized patients with common cancer[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2022, 9(2): 195-199

基金

云南省科技厅科技计划项目(202101AY070001‐024)

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