恶性肿瘤已成为人类健康的最大难题,而肿瘤患者最常见的并发症之一是营养不良,缩短了患者的生存时间,同时 也给社会造成了巨大的负面影响。 因此,如何改善肿瘤患者的营养不良状况有着重要的临床研究意义。 特殊医学用途配方 食品通过科学的配方,根据其不同类型搭配不同的营养成分,具有良好的患者适应性,并且经过肠道进行消化和吸收,可以在 更大程度上保留患者自身的消化吸收功能,可作为一种营养治疗的方式。 针对肿瘤细胞与人体正常细胞在代谢方面有显著 差异这一特点,肿瘤患者的特医食品在为正常细胞提供营养和能量的同时,也能改善肿瘤微环境,扰乱肿瘤的代谢水平,抑制 肿瘤的生长。 然而,目前国内外针对肿瘤患者的特医食品配方尚未形成系统化、个体化、规范化的营养治疗模式,给肿瘤相关 特医食品的发展带来巨大挑战。 本文就肿瘤的特殊医学用途配方食品的研究热点及进展、存在问题、发展现状及国内外营养 不良患者的营养干预进行综述,旨在为肿瘤的特殊医学用途配方食品的基础研究和临床应用提供新的思路。

Malignant tumor has become a serious challenge against fitness of human-being and the most common complication of tumor patients is malnutrition which extremely shortens the survival time of patients. Furthermore society is subject to huge adverse impact. In consequence it is of great significance to improve malnutrition for cancer patients. Food for special medical purpose FSMP is easy to digest and absorb according to different types of nutrients through scientific formula and has good adaptability to patients. It can preserve the digestion and absorption function of patients to a greater extent and can be used as a way of nutritional support. There is prominent discrepancy between tumor cells and normal cells in metabolism. FSMP can provide enough nutrition and energy for normal cells while improving tumor microenvironment disrupting tumor metabolism and inhabiting tumor growth. However at present the formulation of special medical food for cancer patients at home and abroad has not formed a systematic individualized and standardized nutritional treatment mode which brings great challenges to the development of special medical food related to cancer. This article reviews the research hotspots progress existing problems development status and nutritional intervention for malnourished patients at home and abroad aiming to provide new ideas for the basic research and clinical application of tumor-related FSMP.