目的 探究营养助理模式对头颈部肿瘤患者根治性放化疗期间营养方案执行程度、营养状况和身心状态的影响。 方法 收集 2018 年 6 月至 2021 年 12 月南京鼓楼医院肿瘤中心收治的头颈部肿瘤患者,采用随机数字表法将观察对象随机分 为两组,对照组(常规护理模式,n = 72)和干预组(营养助理模式,n = 66)。 所有患者均采用根治性同步放化疗方案。 比较两 组能量和蛋白质的实际摄入量、心理、生活质量和营养指标变化。 结果 治疗过程中,两组能量摄入量减少幅度差异无统计学 意义(P>0. 05),同时干预组蛋白质的摄入量高于对照组,差异有统计学意义(P<0. 05);心理及生活质量方面,医院焦虑抑郁 评估量表(HADS)评分和生活质量量表 Karnofsky 功能状态(KPS)评分,干预组的评分均优于对照组,差异有统计学意义(P< 0. 05);营养指标方面,干预组在体重和血清白蛋白指标上均优于对照组,差异有统计学意义(P<0. 05),而 C 反应蛋白指标两 组无统计学差异(P>0. 05)。 结论 在头颈部肿瘤根治性放化疗中,营养助理模式可能有利于帮助患者维持能量摄入水平,从 而使患者维持较好的营养状况和身心健康状态。

Objective To explore the effects of a nutritional assistant nursing-mode in head and neck cancer patients undergoing radiotherapy whose degree of implementation of nutrition programmes and impact on nutrition status and physical and mental health. Method 138 patients with head and neck cancer in Nanjing Drum Tower Hospital from June 2018 to December 2021 were selected and randomly divided into control group n = 72 and observation group n = 66 . The intervention group patients adopted the nursing-mode of a nutritional assistant role. In the control group was treated with routine nursing-mode. All patients received radical concurrent chemoradiotherapy. Then the nutrient intaking nutritional indexes the degree of anxiety and depression as well as quality of life were compared between the two groups. Result The energies of the two groups were decreased while the indexes of intervention group were better at other time points but there was no statistical significance P> 0. 05 . The proteins intakes of the intervention group were better between two groups P<0. 05 . The HADS and KPS scores of the intervention group were better P< 0. 05 . The indexes of serum albumin and weight in the intervention group were better except CRP P< 0. 05 . Conclusion In the treatment of head and neck cancer the nursing-mode of a nutritional assistant role may help to maintain patients' energy as well as protein intaking. In addition it may also alleviate nutritional status and the physical and psychological healthy states.