摘要
肌肉减少症是一种以骨骼肌力量、含量、质量以及功能下降为主要特征的进行性骨骼肌疾病,好发于老年人、肿瘤
患者及各类慢性病患者。 肌肉减少症显著增加高风险人群的跌倒风险、手术并发症发生率和死亡率,给医疗及社会带来沉重
的负担。 然而,目前肌肉减少症的筛查、诊断标准尚未统一,仍缺乏适合中国人群的系统性和个体化的诊断标准和治疗措施
规范。 本文旨在通过对已发表的肌肉减少症相关研究及指南进行总结,建立具有我国特色的规范化的肌肉减少症筛查标准、
诊断与治疗的流程及体系,适用于我国各级医疗机构开展肌肉减少症的筛查、评估、诊断、治疗与监测,为临床工作人员和研
究者提供参考。
Abstract
Sarcopenia is a progressive skeletal muscle disease characterized by a decline in muscle strength quantity quality and
function. It is commonly observed in elderly individuals cancer patients and those with chronic diseases. Sarcopenia significantly
increases the risk of falls surgical complications and mortality rates among high-risk populations imposing a substantial burden on
both healthcare systems and society. However there is currently no unified screening and diagnostic criteria for sarcopenia and there
is a lack of systematic and individualized diagnostic criteria and standardized treatment measures suitable for the Chinese
population. This article aims to summarize published research and guidelines related to sarcopenia to establish standardized screening
criteria diagnostic and treatment processes and systems with Chinese characteristics. These can be applied in healthcare institutions
at all levels in China for screening assessment diagnosis treatment and monitoring of sarcopenia providing a reference for clinical
practitioners and researchers.
关键词
肌肉减少症 /
老年 /
诊断 /
生活质量 /
远期预后 /
筛查 /
治疗 /
标准
Key words
Sarcopenia /
Elderly /
Diagnosis /
Quality of life /
Long term prognosis /
Screening /
Treatment /
Standard
上海市抗癌协会肿瘤营养与支持治疗专业委员会.
肌肉减少症规范化筛查、评估、诊断、治疗和监测技术标准[J]. 肿瘤代谢与营养电子杂志. 2024, 11(6): 782-787
Shanghai Anticancer Association Oncology Nutrition and Supportive Therapy Professional Committee.
Establishment of standardized screening diagnosis and treatment criteria for sarcopenia and expert recommendations[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2024, 11(6): 782-787
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基金
上海市科技计划项目(21DZ2208300)
上海市中西医结合学会科研基金(shcim202101)