目的 探究基于多维度营养状况评估的食管癌患者营养不良的危险因素分析。 方法 选取 2019 年 3 月至 2023 年 3 月海安市中医院肿瘤科收治的食管癌患者 106 例临床资料开展回顾性分析,通过多维度营养状况评估[全球领导人营养不良 倡议(GLIM)、欧洲肠外肠内营养学会 2015 年营养不良专家共识(ESPEN 2015)及患者主观整体评估(PG-SGA)]评估 106 例 食管癌患者营养状况,通过二元 Logistic 回归分析营养不良的影响因素。 结果 GLIM 评估患者存在 21 例营养不良、ESPEN 2015 评估患者存在 18 例营养不良,PG-SGA 评估患者存在 19 例营养不良,多维度综合评估患者存在 27 例营养不良。 二元 Logistic 回归分析显示,年龄(> 60 岁)、有合并症、有家族史、病理阶段(Ⅲ~ Ⅳ期)、病程(≥ 12 个月)、消化道症状(≥2 条)、 不良饮食行为、卡诺夫斯凯计分(KPS)(<70 分)均是影响食管癌患者营养不良危险因素(P < 0. 05)。 结论 基于多维度营养 状况评估食管癌患者营养状况具有较好临床价值,年龄( >60 岁)、有合并症、有家族史、病理阶段(Ⅲ~ Ⅳ期)、病程(≥ 12 个 月)、消化道症状(≥ 2 条)、不良饮食行为、KPS(< 70 分)均是影响食管癌患者营养不良危险因素,临床需加强重视。

Objective To explore the risk factors of malnutrition in patients with esophageal cancer based on multidimensional nutritional status assessment. Method Clinical data of 106 patients with esophageal cancer admitted to the Oncology Department of Hai'an Hospital of Traditional Chinese Medicine from March 2019 to March 2023 were retrospectively analyzed. Through the global leadership initiative on malnutrition the Global Leadership Initiative on Malnutrition GLIM European Society for Clinical Nutrition and Metabolism 2015 ESPEN 2015 and patient-generated subjective global assessment PG-SGA were used to evaluate the nutritional status of 106 patients with esophageal cancer and the influencing factors of malnutrition were analyzed by binary Logistic regression. Result There were 21 cases of malnutrition assessed by GLIM 18 cases of malnutrition assessed by ESPEN 2015 19 cases of malnutrition assessed by PG-SGA and 27 cases of malnutrition assessed by multidimensional comprehensive assessment. Binary Logistic regression analysis showed that age > 60 years old comorbidities family history pathological stage Ⅲ-Ⅳ course of disease ≥ 12 months gastrointestinal symptoms ≥2 items poor diet behavior and Kanofsky performance score KPS < 70 points were all risk factors for malnutrition in patients with esophageal cancer P < 0. 05 . Conclusion Evaluating the nutritional status of esophageal cancer patients based on multidimensional nutritional status has good clinical value age > 60 years comorbidities family history pathological stage Ⅲ - Ⅳ duration of the disease >12 months gastrointestinal symptoms ≥2 poor dietary behaviors and KPS < 70 are risk factors for malnutrition in patients with esophageal cancer which need to be emphasized more in the clinic.