血清白蛋白水平在肺癌诊疗中的预测价值

李会颖, 谢宇, 林永娟, 俞婷婷, 蒋澄, 尹震宇

肿瘤代谢与营养电子杂志 ›› 2026, Vol. 13 ›› Issue (2) : 324-332.

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肿瘤代谢与营养电子杂志 ›› 2026, Vol. 13 ›› Issue (2) : 324-332. DOI: 10.16689/j.cnki.cn11-9349/r.2026.02.020
综述

血清白蛋白水平在肺癌诊疗中的预测价值

  • 李会颖, 谢宇, 林永娟, 俞婷婷, 蒋澄, 尹震宇
作者信息 +

The predictive value of serum albumin levels in the diagnosis and treatment of lung cancer

  • Li Huiying, Xie Yu, Lin Yongjuan, Yu Tingting, Jiang Cheng, Yin Zhenyu
Author information +
文章历史 +

摘要

肺癌在我国的发病人数和死亡人数均高居恶性肿瘤首位,疾病负担不断加重。除了传统放化疗外,新型靶向药物、免疫药物的不断涌现,肺癌治疗已经进入精准治疗时代。血清白蛋白(ALB)水平降低是肺癌常见并发症,近年来,ALB在肺癌患者临床管理及精准治疗中作用的受到关注。本文综述最新研究,阐述ALB在肺癌发生发展中的预测价值以及在抗肿瘤药物疗效与安全性评估方面的价值,还介绍了“白蛋白相关炎症标志物”和“白蛋白相关营养标志物”对肺癌管理的参考价值,强调关注ALB在肺癌诊疗过程中的重要预测价值。

Abstract

Lung cancer ranks first in incidence and mortality among malignant tumors in China, with an increasing disease burden. In addition to traditional chemoradiotherapy, the continuous emergence of new targeted and immunotherapeutic drugs has ushered lung cancer treatment into the era of precision therapy. Reduced serum albumin (ALB) level is a common complication of lung cancer. In recent years, discussions on the role of ALB in the clinical management and precision treatment of lung cancer patients have been ongoing. This article reviews the latest research, elucidates the predictive value of ALB on the occurrence and progression of lung cancer, as well as the efficacy and safety of antitumor drugs. Furthermore, in addition to ALB as a standalone biomarker, the "albumin-related inflammatory markers" and "albumin-related nutritional markers" which combine ALB with other indicators, also hold reference value for the clinical management of lung cancer patients. This article emphasizes the importance of focusing on ALB in the medical diagnosis and treatment of lung cancer.

关键词

肺癌 / 白蛋白 / 低白蛋白血症 / 诊疗 / 靶向治疗 / 蛋白结合率 / 预后 / 生物标志物

Key words

Lung cancer / Albumin / Hypoproteinemia / Diagnosis and treatment / Targeted therapy / Protein binding ratio / Prognostic / Biomarker

引用本文

导出引用
李会颖, 谢宇, 林永娟, 俞婷婷, 蒋澄, 尹震宇. 血清白蛋白水平在肺癌诊疗中的预测价值[J]. 肿瘤代谢与营养电子杂志. 2026, 13(2): 324-332 https://doi.org/10.16689/j.cnki.cn11-9349/r.2026.02.020
Li Huiying, Xie Yu, Lin Yongjuan, Yu Tingting, Jiang Cheng, Yin Zhenyu. The predictive value of serum albumin levels in the diagnosis and treatment of lung cancer[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2026, 13(2): 324-332 https://doi.org/10.16689/j.cnki.cn11-9349/r.2026.02.020

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