摘要
肺癌是常见肿瘤之一,受摄入减少、手术和靶向药物的影响, 营养不良在肺癌患者中很常见。 肺癌患者应通过营
养风险筛查 2002 与患者主观整体评估进行营养评估。 并非所有接受化疗的肿瘤患者都需要营养治疗,对于营养状况良好的
接受化疗的肺癌患者,不推荐常规应用营养治疗。 肿瘤患者的蛋白质合成和分解代谢均存在异常。 对于进展期肺癌患者,蛋
白质分解大于合成,代谢应激因素也会增加蛋白质的需要量,肺癌患者蛋白质需要量推荐给予 1. 2~ 2. 0 g / (kg·d),能量摄入
目标量推荐为 25~ 30 kcal / (kg·d)。 口服营养补充是肺癌患者首选的营养治疗方式,适用于能够吞咽、胃肠道功能正常的患
者。 对于肠内营养可达到正常营养需要量的肺癌患者,不推荐常规进行肠外营养治疗。 当患者无法通过肠内营养(如严重放
射性食管炎、严重恶心呕吐)获得足够的营养需要时,则应选择补充性肠外营养或全肠外营养。 口服谷氨酰胺可降低肺癌患
者放射性食管黏膜炎的发生率和严重程度。 选用低糖高脂配方可改善慢性阻塞性肺疾病患者血气分析和呼吸功能指标。
Abstract
Lung cancer is one of the most common tumors. Malnutrition is common in patients with lung cancer which is affected
by reduced intake surgery and targeted drugs. They should receive nutritional assessment through Nutritional Risk Screening 2002 and
patient -generated subjective global assessment. Not all cancer patients receiving chemotherapy need nutritional therapy and routine
use of nutritional therapy is not recommended for lung cancer patients receiving chemotherapy with good nutritional status. Protein
synthesis and catabolism are abnormal in tumor patients. For advanced lung cancer patients protein decomposition is greater than
synthesis and metabolic stress factors will also increase the protein requirement. The protein requirement of lung cancer patients is
recommended to be 1. 2 ~ 2. 0 g / kg·d and the target energy intake is recommended to be 25 ~ 30 kcal / kg·d . Oral nutritional
supplement is the preferred nutritional therapy for lung cancer patients suitable for patients who can swallow and have normal
gastrointestinal function. For lung cancer patients whose enteral nutrition can meet the normal nutritional requirements routine
parenteral nutrition therapy is not recommended. When patients cannot meet their nutritional needs through enteral nutrition e. g.
severe radiation esophagitis severe nausea and vomiting supplementary parenteral nutrition or total parenteral nutrition should be
selected. Oral glutamine can reduce the incidence and severity of radioactive esophageal mucositis in lung cancer patients. Low sugar
and high fat formula can improve blood gas analysis and respiratory function indexes in patients with chronic obstructive pulmonary
disease.
关键词
肺癌 /
共识 /
营养治疗
Key words
Lung cancer /
Consensus /
Nutritional therapy
中国抗癌协会肿瘤营养专业委员会,中华医学会肠外肠内营养学分会.
肺癌患者的营养治疗专家共识[J]. 肿瘤代谢与营养电子杂志. 2023, 10(3): 336-341
Chinese Society of Nutritional Oncology, Chinese Society for Parenteral and Enteral Nutrition.
Expert consensus on nutritional treatment for patients with gastroparesis[J]. Electronic Journal of Metabolism and Nutrition of Cancer. 2023, 10(3): 336-341
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基金
北京市科委计划项目(D181100000218004)
国家重点研发计划项目(2022YFC2009600)