再喂养综合征一般是指机体经过长期饥饿或营养不良,重新摄入营养物质后出现以低磷血症为特征的电解质代谢 紊乱,对心脏、肝脏,以及呼吸系统、神经系统与肌肉系统产生不利影响,导致临床并发症甚至死亡。 对于严重营养不良的患 者,再喂养综合征是一种潜在的致命并发症。 在不同的医院住院患者中,再喂养综合征的发生率在 0. 43% ~ 34%,接受营养治 疗的肿瘤患者中再喂养综合征发生率可高达 25%左右。 再喂养综合征的发病机制、病理生理改变与胰岛素抵抗、电解质向细 胞内转移和合成代谢增强有关。 本文基于现有研究和证据,结合临床经验,就肿瘤患者再喂养综合征的判断及治疗等作总结 和推荐。

Refeeding syndrome generally refers to the electrolyte metabolism disorder characterized by hypophosphatemia after the body re-ingestion of nutrients after a long period of hunger or malnutrition which adversely affects the heart liver respiratory system nervous system and muscular system leading to clinical complications and even death. For severely malnourished patients refeeding syndrome is a potentially fatal complication. The incidence of refeeding syndrome among hospitalized patients in different hospitals ranges from 0. 43% to 34% and among tumor patients receiving nutritional treatment the incidence of refeeding syndrome can be as high as about 25%. The pathogenesis pathological and physiological changes of refeeding syndrome are related to insulin resistance electrolyte transfer to cells and enhanced synthetic metabolism. Based on existing research and evidence combined with clinical experience this article summarizes and recommends the diagnosis and treatment of tumor patients with refeeding syndrome.